Introduction

In 2024, the United States leads the global digital health ecosystem, driven by a robust landscape of ventures, investors, and partnerships that are shaping the future of healthcare. With the largest number of digital health startups worldwide and the highest venture survival rates, the U.S. continues to be a key player in advancing healthcare technology. Leveraging proprietary data from Galen Growth’s HealthTech Alpha platform, the analysis covers critical aspects such as venture survival rates, clinical evidence, and the role of partnerships in driving innovation and growth.

Key Messages from the US Digital Health Key Trends 2024

1. Ecosystem Size and Survival Rate: The U.S. hosts the largest global digital health ecosystem with 3,724 ventures founded domestically and 1,117 international ventures operating in the U.S. The survival rate of U.S. digital health ventures is 97%, surpassing the global average of 93%.
2. Investment Activity: Over 6,300 investors have participated in digital health funding rounds in the U.S., with Khosla Ventures, General Catalyst, and Andreessen Horowitz leading the way.
3. Key Categories in Digital Health: Health management solutions (17%), patient solutions (12%), and medical diagnostics (10%) form the core categories, reflecting an emphasis on improving healthcare workflows, patient care, and diagnostics.
4. Partnership Growth: The U.S. has witnessed stable partnership growth, with nearly 6,800 partnerships announced from 2020 to 2024, a significant number involving health systems and other digital health ventures.
5. Clinical Evidence and Regulatory Approvals: 25% of U.S. ventures demonstrate strong clinical evidence, with oncology leading the therapeutic areas. The U.S. has also produced over 17,400 peer-reviewed publications since 2014 and 31 regulatory approvals in 2024 YTD.

This overview captures the U.S. digital health sector’s resilience and innovation, underscored by strong investment flows, a focus on disease-specific solutions, and robust partnership ecosystems.

Also read our China Digital Health Key Trends 2024.