TL;DR

  • Total Funding: H1 2024 saw a robust digital health funding surge with $9.6 billion invested across 414 deals, demonstrating resilience and growth against a previously anticipated funding winter.
  • Regional Funding Dominance: North America’s share of global digital health funding rose to 77% in H1 2024, a nine-percentage point increase year over year, reflecting its leading position in the sector.
  • Health System Partnerships: Health systems increased the number of partnerships with digital health ventures, accounting for 23% of all collaborations, underscoring the integration of digital solutions and AI technology in traditional healthcare settings.
  • TechBio Investments: TechBio (Research Solutions) led digital health funding with $2.2 billion of investment across 28 deals, followed by $1.4 billion in Health Management Solutions, highlighting the surge in AI-driven healthcare and research tools.
  • AI in Digital Health: AI-driven solutions constituted 58% of total digital health funding, with significant investments in research and healthcare tools, though only 42% of US ventures leverage AI technology.
  • Mental Health Funding: Mental health attracted $1.34 billion in funding, a 63% year-over-year increase, reclaiming its position as the top-funded therapeutic area, followed by oncology ($1.28B) and neurology ($924M).

Contrary to the anticipated prolonged funding winter, the first half of 2024 marked a surprising resurgence in North America’s digital health ecosystem. Total investments across the United States, Canada, and Mexico reached a remarkable $9.6 billion, spread across 414 deals, representing a 13% year-over-year increase from H1 2023’s $8.6 billion. This upsurge reflects renewed investor confidence and a burgeoning momentum in the sector.

Investment Trends: A Robust Rebound in U.S. Digital Health

The digital health sector witnessed a strong quarter, primarily driven by two innovation hubs: TechBio and Health Systems. TechBio, focusing on digital health solutions for biopharma, attracted significant investments spurred by the implementation of foundational models (aka. GenAI). These models have revolutionised the biopharma landscape, allowing for more efficient and effective research and development processes. Health Systems, capturing 25% of digital health partnerships, intensified efforts to tackle pressing challenges in healthcare. These collaborations underscore the vital integration of digital solutions in traditional healthcare, enhancing patient outcomes and operational efficiencies.

As venture capital inflows regained momentum in H1 2024, funding stress is gradually easing. Notably, the proportion of Growth Stage ventures securing funding in the past 18 months has risen by 2% quarter-over-quarter in North America since Q3 2023 to reach 42%. This trend indicates a stabilising environment and increasing investor confidence in the potential of more mature startups, suggesting a positive outlook for the remainder of 2024.

Surpassing Expectations: Digital Health Funding Breakdown in the U.S.

Digital Health Funding in North America
Digital Health Funding in North America finally realized a gain, with a year-on-year increase of 13% from H1 2023 to H1 2024.

The first half of 2024 saw total funding of $9.6 billion across 414 deals in North America. This remarkable performance highlights the resilience and potential of the digital health sector. The regional share of global venture funding increased to 77%, a significant rise from the previous year’s 68%. This growth underscores North America’s dominant global digital health market position. AI-driven innovations continue to play a pivotal role, with 58% of the total funding allocated to ventures leveraging AI, particularly in the Research Solutions (aka TechBio) Cluster, which accounted for 40% of this AI-focused investment. Read Galen Growth’s full report on Digital Health in Biopharma Research for a deep-dive into this Cluster.

The United States dominated the funding landscape, accounting for an overwhelming 99% of the total investments in North America. This reflects the country’s leadership in digital health innovation and investment. Canada and Mexico, although contributing minimally, show a growing interest in digital health innovations, indicating potential future growth areas in these markets.

Regional Insights: California Leading the Charge in Digital Health Investments

California emerged as the frontrunner, securing 44% of the US funding. The state’s strong innovation ecosystem, world-class universities, and leading technology companies make it a hotbed for digital health investments. New York followed with 19%, reflecting its significant healthcare infrastructure and growing tech scene. Massachusetts, with 7%, also demonstrated its leadership in biotech and digital health innovation.

Sector Highlights: Mental Health Takes Centre Stage in Digital Health Funding

Mental Health regained prominence in H1 2024, attracting the highest funding among disease-specific ventures with $1.34 billion, representing a 63% year-over-year increase. This surge underscores the continuing recognition of mental health issues and the critical need for innovative solutions that are reimbursed in this space. Oncology followed closely with $1.28 billion, a 48% increase from the previous year, highlighting continued investor interest in cancer treatments and diagnostics. Neurology, another key area, saw $924 million in funding, reflecting ongoing advancements and investments in neurological health solutions.

This shift towards mental health indicates a broader trend within the healthcare industry, recognising the importance of mental well-being as an integral part of overall health. Explore Mental Health ventures in HealthTech Alpha. The substantial investment in oncology and neurology also highlights the continued focus on developing cutting-edge treatments and technologies for these critical areas.

Top 10 Therapeutic Areas by Funding Value in H1 2024
Oncology and mental health emerged as the top-funded therapeutic areas in North America during H1 2024, as depicted in this bubble chart.

AI and Partnerships: The Driving Forces in US’s Digital Health Ecosystem

AI-Driven Innovations

Share of venture capital investment in AI ventures, 2020-H1 2024

Investments in AI-driven ventures have steadily risen, constituting a significant share of the total funding. In H1 2024, ventures leveraging AI accounted for 58% of the total funding in North America, underscoring the increasing reliance on AI technologies to enhance healthcare delivery and research. The integration of AI in digital health has revolutionised the sector, enabling more precise diagnostics, personalised treatments, and efficient operational processes.

AI-driven solutions, particularly within the TechBio segment, attracted substantial investments. This focus on AI highlights its critical role in driving innovation and improving healthcare outcomes. Investors are keenly aware of the transformative potential of AI, leading to increased funding and support for AI-centric ventures. Read Galen Growth’s full report on AI in Digital Health.

Surge in Partnerships

Q2 2024 witnessed a substantial increase in partnerships, with 900+ recorded for US ventures. Health Systems have intensified their efforts to address pressing challenges by doubling down on partnerships with digital health ventures, forging a 23% share of all collaborations. This underscores the necessary and growing integration of digital solutions in traditional healthcare settings, especially those leveraging AI technology. Read Galen Growth’s full report on U.S. Health Systems for a deep-dive into this critical sector.

While seeing a slight decline in its share of global partnerships, North America remains a critical hub. Venture-to-venture partnerships were predominant, accounting for 24% of all alliances. This surge in partnerships reflects the collaborative nature of the digital health sector, where companies join forces to leverage each other’s strengths, resources, and expertise. 

Growth of Partnerships in North America and Rest of World by Quarter
North America has consistently outpaced the rest of the world in partnership growth from Q1 2020 to Q2 2024, maintaining a significant share of global partnerships.

Understanding Alpha Forecaster’s Value

A noteworthy tool contributing to this optimistic outlook is the Alpha Forecaster. This predictive analytics tool has been instrumental in identifying ventures with above-average potential. By leveraging vast datasets and advanced algorithms, Alpha Forecaster evaluates market trends, financial health, and growth potential of digital health ventures. Its insights have been pivotal for investors, allowing them to pinpoint high-value opportunities and mitigate risks effectively.

Noteworthy Deals and Emerging Ventures in U.S. Digital Health

Several noteworthy deals in H1 2024 highlight the growing investor interest in innovative digital health solutions. Xaira Therapeutics secured a strategic investment of $1 billion, underscoring the potential of AI-driven drug discovery and development. Freenome, specialising in early cancer detection, raised $254 million in a Series E funding round, reflecting the ongoing interest in oncology diagnostics. Learn more about Freenome on HealthTech Alpha. Blackrock Neurotech, a leader in neurotechnology, received $214 million in strategic funding, emphasising the advancements and investments in neurological health. Learn more about Blackrock Neurotech on HealthTech Alpha.

These deals illustrate the diverse and dynamic nature of the digital health sector. Investors are not only focusing on established areas like oncology but also exploring emerging fields such as neurotechnology and AI-driven research solutions. This diversity in investment highlights the sector’s broad potential and the wide range of opportunities available.

A Promising Horizon for Digital Health in the U.S.

The first half of 2024 has unequivocally demonstrated the resilience and growth potential of North America’s digital health ecosystem. The sector is poised for continued expansion with robust investments, a surge in partnerships, and a strong focus on AI-driven solutions. 

However, the ongoing IPO drought continues to cause concern about the sustainability of this resurgence. As funding stress eases and innovative ventures continue to emerge, the digital health landscape in North America promises a dynamic and prosperous future.

Investors, innovators, and healthcare providers are recognising digital health technologies’ transformative potential. The trends and insights from H1 2024 suggest a promising horizon, with North America leading the way in digital health innovation and investment. As we progress, the sector is expected to grow further, driven by continued advancements in AI, increased collaboration, and a sustained focus on addressing critical healthcare challenges.

About Galen Growth

Galen Growth is a preeminent global digital health intelligence, analytics, and advisory firm. With a mission to unlock the full potential of the digital health ecosystem, Galen Growth provides unparalleled insights and data-driven strategies to stakeholders worldwide. Their extensive services include market analysis, venture capital trends, and strategic advisory, making them an invaluable partner for investors, startups, and corporates aiming to navigate and excel in the digital health landscape. By leveraging its comprehensive network and proprietary tools, Galen Growth bridges the gap between innovation and industry, fostering growth and facilitating impactful partnerships. 

Source

This blog is based on the “Galen Growth Mid-Year 2024 U.S. Digital Health Ecosystem Key Trends Report,” which features over 80 pages of data, charts, and insights. The report provides data-driven, non-biased, and non-hype analysis, unrivalled in its ability to go beyond just funding data. This comprehensive report is available to all our Premium customers. For more details, visit Galen Growth.