Unveiling the 4th Edition of the HT50 Core Investors Report

Navigating the digital health capital landscape requires more than just following the money—it requires following the smart money.

In a market that has demonstrated remarkable resilience, attracting USD 164B across 10,100+ deals since 2021, identifying the true leaders is critical. This exclusive 2025 report moves beyond simple deal counts to rank investors based on portfolio maturity, innovation, and partnership strength.

Powered by HealthTech Alpha—the world’s leading private market data platform with coverage of over 16,100 digital health ventures —this report provides the definitive ranking of the investors defining the future of healthcare.

What’s Inside the Report?

1. The 2025 Rankings

Discover who claimed the top spots across key sectors and regions:

• Global Leaders: See which firms dominate the Early, Growth, and Late-stage investment landscapes.

• Regional Powerhouses: Detailed breakdowns of the top investors in Europe, North America, and Asia Pacific .

• Thematic Champions: Who is funding the breakthroughs in TechBio, Femtech, and Clinical Trials? .

2. Critical Market Trends

• The Resilience Factor: Despite tighter macroeconomic conditions, 2025 capital deployment is projected to exceed 2024 levels, signaling a durable growth phase.

• Partnerships Over Capital: Collaborations have grown at a 14.4% CAGR since 2021. Learn why partnerships are now the primary catalyst for adoption and market penetration.

• The Shift to Quality: While early-stage deals still lead, investors are shifting focus toward growth-stage ventures with proven commercial traction.

3. The Winners’ Circle

Get unmatched insights into the portfolios of the award-winning investors:

• Early-Stage Winner
• Growth-Stage Winner
• Late-Stage Winner
• Europe Region Winner
• Femtech Winner and more

Why This Report Matters

• Data-Driven Methodology: Unlike opinion-based lists, these rankings are derived from the Alpha Score™ and Partnership Score™. These proprietary metrics evaluate venture maturity (Momentum, Money, Market, Innovation) and ecosystem interconnectedness.

• Global Scope: With 56% of active investors in North America, 26% in Europe, and 15% in Asia Pacific, this report provides a truly global perspective on where capital is flowing.

• Actionable Intelligence: Whether you are a startup seeking funding, an investor benchmarking performance, or a corporate leader looking for partners, this report identifies the key stakeholders you need to know.

About the Data

The report is powered by HealthTech Alpha, the premier digital health intelligence platform delivering unparalleled data and insights into the evolving healthcare technology landscape. Leveraging an extensive database of over 16,000 ventures and cutting-edge analytics, HealthTech Alpha provides a data-driven foundation to analyse the critical trends shaping the future of digital health.

Designed to empower stakeholders—including investors, pharmaceutical leaders, and medical device manufacturers—HealthTech Alpha offers actionable intelligence to navigate digital transformation complexities. This collaboration ensures readers gain a comprehensive, evidence-based view of the intersection between digital health and healthcare, equipping them to identify strategic opportunities, assess market dynamics, and stay ahead in this fast-evolving industry.